|
KMID : 0380020050200010001
|
|
Korean Journal of Biotechnology and Bioengineering
2005 Volume.20 No. 1 p.1 ~ p.11
|
|
|
The Use of Stem Cells as Medical Therapy
|
|
Son Eun-Wha
Pyo Suhk-Neung
|
|
|
Abstract
|
|
|
|
Recently, there has been extremely active in the research of stem cell biology. Stem cells have excellent potential for being the ultimate source of transplantable cells for many different tissues. Researchers hope to use stem cells to repair or replace diseased or damaged organs, leading to new treatments for human disorders that are currently incurable, including diabetes, spinal cord injury and brain diseases. There are primary sources of stem cells like embryonic stem cells and adult stem cells. Stem cells from embryos were known to give rise to every type of cell. However, embryonic stem cells still have a lot of disadvantages. First, transplanted cells sometimes grow into tumors. Second, the human embryonic stem cells that are available for research would be rejected by a patient’s immune system. Tissue-matched transplants could be made by either creating a bank of stem cells from more human embryos, or by cloning a patient’s DNA into existing stem cells to customize them. However, this is laborious and ethically contentious. These problems could be overcome by using adult stem cells, taken from a patient, that are treated to remove problems and then put back. Nevertheless, some researchers do not convince that adult stem cells could, like embryonic ones, make every tissue type. Human stem cell research holds enormous potential for contributing to our understanding of fundamental human biology. In this review, we discuss the recent progress in stem cell research and the future therapeutic applications.
|
|
|
KEYWORD
|
|
|
Stem cell, embryonic stem cell, adult stem cell, mesenchymal stem cell, medical therapy
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|